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1.
Endocrinol Diabetes Nutr ; 64(5): 250-257, 2017 May.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-28495320

RESUMO

OBJECTIVE: Glycemic variability is an independent predictor of mortality in critically ill patients. The objective of this study was to compare two intravenous insulin protocols in critically ill patients regarding the glycemic variability. MATERIAL AND METHODS: This was a retrospective observational study performed by reviewing clinical records of patients from a Critical Care Unit for 4 consecutive months. First, a simpler Scale-Based Intravenous Insulin Protocol (SBIIP) was reviewed and later it was compared for the same months of the following year with a Sliding Scale-Based Intravenous Insulin Protocol (SSBIIP). All adult patients admitted to the unit during the referred months were included. Patients in whom the protocol was not adequately followed were excluded. A total of 557 patients were reviewed, of whom they had needed intravenous insulin 73 in the first group and 52 in the second group. Four and two patients were excluded in each group respectively. RESULTS: Glycemic variability for both day 1 (DS1) and total stay (DST) was lower in SSBIIP patients compared to SBIIP patients: SD1 34.88 vs 18.16 and SDT 36.45 vs 23.65 (P<.001). CONCLUSION: A glycemic management protocol in critically ill patients based on sliding scales decreases glycemic variability.


Assuntos
Glicemia/análise , Estado Terminal , Insulina/administração & dosagem , APACHE , Adulto , Idoso , Protocolos Clínicos , Contraindicações de Medicamentos , Feminino , Humanos , Infusões Intravenosas/métodos , Insulina/uso terapêutico , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
2.
Endocrinol. diabetes nutr. (Ed. impr.) ; 64(5): 250-257, mayo 2017. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-171714

RESUMO

Objetivo: La variabilidad glucémica es un predictor independiente de la mortalidad en pacientes críticos. El objetivo del presente estudio es comparar 2 protocolos de administración de insulina intravenosa en críticos en cuanto a la variabilidad glucémica se refiere. Material y métodos: Se trata de un estudio observacional retrospectivo realizado mediante revisión de historias clínicas de los pacientes de una unidad de críticos durante 4 meses consecutivos. Primero se revisó un protocolo de insulina más simple o protocolo de insulina intravenosa basado en una escala (PIVBE), que fue comparado con los mismos meses del siguiente año donde se utilizó protocolo insulina intravenosa basado en escalas dinámicas (PIVBED). Se incluyó a todos los pacientes, adultos, ingresados en la unidad durante los meses referidos. Se excluyó a los pacientes en los que el protocolo no se siguió correctamente. Se revisó a 557 pacientes, de los cuales habían necesitado insulina intravenosa 73 en el primer grupo y 52 en el segundo. Fueron excluidos 4 y 2 pacientes en cada grupo, respectivamente. Resultados: La variabilidad glucémica tanto del primer día (DS1) como la total de la estancia (DST) fue menor en aquellos pacientes tratados con el PIVBED frente al PIVBE: DS1 34,88 frente a 18,16 y DST 36,45 frente a 23,65 (p<0,001). Conclusión: Un protocolo de manejo de glucemia en pacientes críticos basado en escalas dinámicas disminuye la variabilidad glucémica (AU)


Objective: Glycemic variability is an independent predictor of mortality in critically ill patients. The objective of this study was to compare two intravenous insulin protocols in critically ill patients regarding the glycemic variability. Material and methods: This was a retrospective observational study performed by reviewing clinical records of patients from a Critical Care Unit for 4 consecutive months. First, a simpler Scale-Based Intravenous Insulin Protocol (SBIIP) was reviewed and later it was compared for the same months of the following year with a Sliding Scale-Based Intravenous Insulin Protocol (SSBIIP). All adult patients admitted to the unit during the referred months were included. Patients in whom the protocol was not adequately followed were excluded. A total of 557 patients were reviewed, of whom they had needed intravenous insulin 73 in the first group and 52 in the second group. Four and two patients were excluded in each group respectively. Results: Glycemic variability for both day 1 (DS1) and total stay (DST) was lower in SSBIIP patients compared to SBIIP patients: SD1 34.88 vs 18.16 and SDT 36.45 vs 23.65 (P<.001). Conclusion: A glycemic management protocol in critically ill patients based on sliding scales decreases glycemic variability (AU)


Assuntos
Humanos , Masculino , Feminino , Idoso , Idoso de 80 Anos ou mais , Protocolos Clínicos , Insulina/uso terapêutico , Administração Intravenosa , Hiperglicemia/tratamento farmacológico , Índice Glicêmico , Estudos Retrospectivos , Cuidados Críticos/normas , 28599
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